Clinical Testing Services
Clinical Testing Services
YuceOne® Plus Series
YuceOne® Plus Series
Gene Test for Precise Medication for Solid Tumors
Gene Test for Precise Medication for Solid Tumors

The Plus series cover 1267 genes for targeted therapy, chemotherapy, immunotherapy, and genetic risks. Using next-generation sequencing (NGS) technology of target gene capture, it comprehensively and accurately detects target gene capture exons and single nucleotide variations (SNV), short fragment insertion or deletion variations (InDel), gene copy number variations (CNV), and gene rearrangement/fusion within the intron range of standard spliceosomes. It also evaluates TMB, MSI, TNB, HLA LOH and high-quality neoantigen sequences. Using immunohistochemistry (IHC) technology, it detects the representative indicators of tumor immune-microenvironment such as PD-L1 and CD8+TIL, to provide reference and guidance for clinical medication and genetic risk of solid tumor patients.

Product Advantages

▪ Covers 116 genes related to targeted therapy for solid tumor that have been approved by FDA/NMPA, recommended in NCCN guidelines, or have shown clinically significant potential in clinical trials, and evaluates multiple targeted drugs for solid tumor that have been approved or in phase II/III clinical trials

▪ Covers genes related to multiple signaling pathways for tumor occurrence and development

▪ Covers 40 (37 in the blood/body fluid edition) HRR genes. Combined with HRD score test, it comprehensively assesses HRD status and the efficacy of PARP inhibitors

▪ Has the only neoantigen algorithm in China validated by the Tumor Neoantigen Selection Alliance (TESLA)

▪ The blood edition/body fluid edition bTMB uses a machine learning model, which is highly consistent with the tissue TMB (0.90)

▪ Covers 109 chemotherapy genes related to Asian/Chinese populations and assesses the efficacy and toxicity risks of chemotherapy drugs

▪ The mutation information is accurately described according to the HGVS standard terms. The germline genetic mutations are classified according to the ACMG guidelines for the classification of the pathogenicity of mutations, and the clinical medication is suggested based on clinical based medical evidence

▪ Ultra-high depth sequencing and the limit of detection of ctDNA is 0.1%

▪ Covers gene germline interpretation and prompts genetic risks

Product List
YuceOne® Plus
Test of 1267 genes for precise medication for solid tumors
YuceOne® Plus +
Test of 1267 genes for precise medication for solid tumors + PD-L1 expression test
YuceOne® Plus X
Test of 1267 genes for precise medication for solid tumors + PD-L1 expression test + CD8 TIL test
YuceOne® Plus NI
Test of 1012 genes for precise medication for solid tumors (blood edition)
YuceOne® Plus TY
Test of 1012 genes for precise medication for solid tumors (body fluid edition)
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