The Langyukang® series cover genes for targeted therapy and chemotherapy drugs. Using next-generation sequencing (NGS) technology of target gene capture, it comprehensively and accurately detects target gene capture exons and single nucleotide variations (SNV), short fragment insertion or deletion variations (InDel), gene copy number variations (CNV), and gene rearrangement/fusion within the intron range of standard spliceosomes, to provide reference and guidance for the clinical dosing regimens of lung cancer patients.
▪ Covers genes related to targeted therapy for lung cancer that have been approved by FDA/NMPA, recommended in NCCN guidelines, or have shown clinically significant potential in clinical trials, and evaluates multiple targeted drugs for lung cancer that have been approved or in phase II/III clinical trials
▪ Covers 42 lung cancer chemotherapy genes related to Asian/Chinese populations and assesses the efficacy and toxicity risks of lung cancer-related chemotherapy drugs
▪ The mutation information is accurately described according to the HGVS standard terms. The germline genetic mutations are classified according to the ACMG guidelines for the classification of the pathogenicity of mutations, and the clinical medication is suggested based on clinical based medical evidence
▪ Ultra-high depth sequencing and the limit of detection of ctDNA is 0.1%
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